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Friday, October 26, 2007

Rheumatology Conference Dubai

Musculoskeletal Conference 200828 January 2008
This year’s musculoskeletal conference hopes to bring together practitioners from different medical fields, including the general physicians, orthopedic doctors, rheumatologists, women’s health doctors, endocrinologists and all who deal with these issues with their patients daily.
Day 1: 28 January 2008
09:00
Opening remarks by Chairperson: Dr. Humeira Badsha, Specialist Rheumatologist, Dubai Bone & Joint Center, Dubai, UAE


09:10
Rheumatoid Arthritis – State of the Art update


09:30
Beyond RA – Review of Psoriatic Arthritis, Ankylosing Spondylitis and other inflammatory Arthritis


09:50
Disease Modifying Drugs in RA; How the GP can use these drugs and monitor for toxicity Dr. Christopher J. Edwards, Consultant Rheumatologist & Honorary Senior Lecturer, Southampton General Hospital, Southampton University Hospitals NHS Trust & The London Lupus Clinic, London Bridge Hospital, UK


10:10
Anti-TNF Drugs – Safety and Efficacy Updates


10:30
New Frontiers in the treatment of RA – Rituximab, Abatacept and more


10:50
Coffee Break


11:30
Lupus – diagnosis and Management


11:50
Pregnancy and rheumatic drugs


12:10
Management of the pregnant patient with Anti-phospholipid syndromeDr. Graham R V Hughes MD FRCP, Head, Lupus Unit, St Thomas' Hospital, UK


12:30
Lunch (12:30 – 14:00 Joint Injection Workshop)


14:00
Back pain – Red Flags and Non-Surgical management


14:20
Pain Management – Update on safety of NSAIDs and Cox-2 inhibitors


14:40
Gout – Guidelines and use of drugs: From colchicines to Febuxostat


15:00
The New Science of Osteoarthritis: What this means in managing our patientsDr. TW Starz, University of Pittsburgh Medical Centre, Pittsburgh, Pennsylvania, USA


15:20
Coffee Break


15:50
Osteoporosis and interpretation of the DEXA scan. Common errors, artifacts and quality issues


16:10
Bisphosphonates: The backbone of Osteoporosis Management


16:30
How to use the new drugs for Osteoporosis: Strontium, Teriparatide, and more!


16:50
The Epidemic of Vitamin D deficiency and implications beyond bone health: How do we manage severe vitamin D deficiency?Dr. Abdullah Al Arifi, Consultant, Endocrinologist, Department of Medicine; Associate Executive Director, Academic & Training Affairs, CME Section; King Faisal Specialist Hospital & Research Centre, Riyadh, KSA.


17:10
Closing remarks

Monday, October 22, 2007

Rheumatoid Arthritis UAE

In a study of 100 patients at Dubai Bone and Joint Center by Dr. Humeira badsha it was found that the majority of the patients coming to her had very active disease, there was a delay in diagnosis and delay to starting the right treatment. Many patients had seen several doctors withoout the correct diagnosis.

Rheumatology UAE

As part of its ongoing commitment to raising the standards of musculoskeletal treatment and research in the UAE, doctors from the Dubai Bone and Joint Center will be taking a leadership role by chairing several congresses and running workshops at Arab Health Congress 2007.
Dr. Humeira Badsha American Board certified Rheumatologist at Dubai Bone & Joint center will be chairing the Rheumatology congress: Management of Rheumatic Diseases, running from the 31st of January to February 1st. and aims to educate Rheumatologists on the latest advances in the field. The conference is a new addition to the Arab Health portfolio and will be attended by doctors from UAE, Lebanon, Oman, Qatar, Saudi Arabia Jordan, Egypt, Kuwait, UK, USA, Germany and Switzerland.
In addition, a special hands-on workshop on joint injection techniques will be running on February 1st. "Joint and tendon injections are an important skill for every primary care physician," explained Dr. Humeira Badsha, Rheumatology specialist, Dubai Bone and Joint Center. "The workshop will use life size manikins and will focus on a variety of different techniques," she added.

Joint problems UAE

Successful First Step Taken as Bone and Joint Health Week Comes To An End
20 May 2007
Dubai 19th May 2007: Over 450 participants attended the Free Bone Health Day held in Jumeriah Beach Hotel yesterday. The event organized by the Dubai Bone and Joint Center aimed to raise awareness through various educational activities of bone and joint health.
According to Suzanne El Houby, CEO of Dubai Bone and Joint Centre, “the impetus for holding this event was to raise the awareness of bone health and the importance of living a healthy lifestyle. Our center sees a number of patients with fractures resulting from Osteoporosis and we would like to see this number reduced”. The event featured free bone screening for osteoporosis through bone scan ultrasound, alongside lectures on nutrition, arthritis management, osteopathy and physiotherapy.
It is estimated that 70% of post menopausal women in the Emirates have Osteoporosis, as the population ages there will be an increasing number of people affected. According to Dr. Humeria Badsha, Specialist Rheumatologist at Dubai Bone and Joint Center, “It is important to address this condition now, and to educate the younger generation to start eating correctly to ensure that their bone mass is built up to a sufficient level”.
The day began with lectures on Osteoporosis and Arthritis. Sufferers of Arthritis were shown exercises that can help and improve movement. This is a debilitating disease, and its effects have also far reaching emotional consequences. Participants also heard from a nutritionist on the benefits of leading a healthy lifestyle. The consequences of leading an unhealthy lifestyle leads to obesity and its related conditions but it also has an enormous impact on our bones and joints. Exercise is vitally important for our bones and joints, Power Bhangra classes were given, showing alternative forms of exercise that can be fun. Running techniques were demonstrated and how incorrect technique can outweigh the health benefits it offers. Repetitive back strain was addressed with demonstrations on correct posture when sitting at your computer.
This event was part of the Bone Health Week a campaign, which will run annually throughout the Emirates to educate on development of and maintenance of healthy bones and joints.

Osteoporosis UAE

UAE Residents Need to Get Out in the Sun More
24 May 2007
High Level of Osteopenia and Osteoporosis detected in recent screening programmes
Dubai, 24th May 2007: The last phase of the Bone Screening Campaign for osteoporosis took place at Al Ittihad Primary Care Center in Jumeirah in which 110 women and men were screened, and the overall results of the campaign so far confirmed doctor's fears. People are not eating the correct diet to build bone mass nor getting adequate sun with Vitamin D and are therefore leaving themselves more prone to osteoporosis and other bone conditions later in life.
The recent initiative by Dubai Bone and Joint Centre to conduct mass screening in the Emirates with the Ministry of Health (MoH) has produced some alarming statistics. Of those screened on Bone Health Day in the Jumeirah Beach Hotel , 36% had low bone density or osteopenia, which is generally considered the first step along the road to osteoporosis. This is a very serious condition in which bone density is extremely low and bones are porous and prone to shatter. A further 20% of those screened had a measurement of less than -2.5 indicating osteoporosis. This disease results in a significant risk of fracture, the consequences of which can include hospitalization, immobility, and a decrease in the quality of life.
The most alarming statistic was that 32% of men at the recent Hor Al Anz screening had low bone density. The key findings of the most recent screening showed that 36% of post menopausal women were osteopenic and 6% osteoporotic; and amongst young women (< 45 years) 16 % have low bone mass of which 5 % had osteoporosis.
By measuring bone density, it is possible to predict fracture risk in the same manner that measuring blood pressure can help predict the risk of stroke. The results from the screening can then be used to aid a decision as to whether prescription medicine is needed to help reduce the risk of fractures in the future. From a larger perspective, it can be seen that osteoporosis is a costly disease in terms of the healthcare system and time lost from work.
According to Dr. Humeira Badsha, Specialist Rheumatologist at Dubai Bone and Joint Center, “these results are extremely worrying. We saw a woman of 24 who had osteopenia, which is very unusual. It is imperative that UAE residents, both men and women start consuming more calcium rich food and exposing themselves to the sun for a short period of time every day”.
The second phase of the nationwide osteoporosis screening will reassume in September 2007. The National Screening Campaign will include the rest of the Northern Emirates Sharjah, Ajman, Ras Al Khaimah, Fujarah, etc... Exact dates and locations will be announced in mid-august. Dr. Mariam Matar, Assistant Undersecretary of Preventative Medicine for Public Health and Primary Health Care at the MoH recently announced at the launch of Bone Health Week, the seriousness of this condition and how the MoH is attempting to tackle this problem.

Wednesday, September 19, 2007

Dr. Humeira Badsha Publications

Articles - Peer Reviewed:

1. Badsha H, Gunes B, Grossman J, Brahn E. Troponin I assessment of cardiac involvement in patients with connective tissue disease and an elevated creatine kinase MB isoform. J. Clin Rheum. 3 : 131-134, 1997.

2. Tsao BP, Cantor RM, Kalunian KC, Chen CJ, Badsha H, Singh R, Wallace DJ, Kitridou RC, Chen SL, Shen N, Song YW, Isenberg DA, Yu CL, Hahn BH, Rotter Jl. Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus. J Clin Invest 1997 Feb 15; 99 (4) : 725-31.

3. Melioidosis in systemic lupus erythematosus: the importance of early diagnosis and treatment in patients from endemic areas. H Badsha, CJ Edwards, HH Chng. Lupus. 2001;10(11):821-23

4. Low-dose pulse methylprednisolone for systemic lupus erythematosus flares is efficacious and has a decreased risk of infectious complications. Badsha H; Kong KO; Lian TY; Chan SP; Edwards CJ; Chng HH Lupus, 15 August 2002, vol. 11, no. 8, pp. 508-513(6)

5. Mycobacterium haemophilum infection in an SLE patient on mycophenolate mofetil Cheng Lay Teh, Kok Ooi Kong, Angela Chong, Humeira Badsha Lupus. 2002;11(4):249-52.

6. Intravenous pulses of methylprednisolone for SLE. Badsha H,Edwards CJ. Seminars in Arthritis and Rheumatism vol 32, no 5 april 2003 pp

7. Intermittent epoprostenol infusion in systemic lupus erythematosus associated pulmonary hypertension – a series of 3 cases. Kok Ooi Kong, Humeira Badsha, Julian Thumboo, Hiok Hee Chng. Annals Academy of Medicine Singapore January 2003,vol 32 no. 1 pp 118-21

8. Hospitalization of individuals with systemic lupus erythematosus: characteristics and predictors of outcome Edwards CJ, Lian TY, Badsha H, Te CL, Arden N, Chng HH.
Lupus . 2003; 12(9):672-6.

9. Usefulness of serum soluble CD38 and CD 157 levels in differentiating SLE, RA and healthy adults and their relationship with disease activity. Kong KO, Leung BP, Chng HH, Thong BY, Koh ET, Leong KP, Badsha H, Lian Ty, Khoo KM, Howe HS. Ann Acad of Med Singapore 2003 sep; 32 (5 suppl) S16-7

10. Low-dose pulse methylprednisolone is an effective therapy for severe SLE flares.Lupus. 2004;13(3):212-3 Kong KO, Badsha H, Lian TY, Edwards, CJ, Chng HH

11. Pulmonary Haemorrhage in Systemic Lupus Erythematosus H Badsha, CL The, KO Kong, TY Lian, HH Chng. Seminars in Arthritis and Rheumatism 33/6 pp. 414-421

12. Transforming growth factor beta-1 and gene polymorphisms in oriental ankylosing spondylitis. Rheumatology (Oxford). 2005 Jan;44(1):51-4 Howe HS, Cheung PL, Kong KO, Badsha H, Thong BY, Leong KP, Koh ET, Lian TY, Cheng YK, Lam S, Teo D, Lau TC, Leung BP

13. Psychometric properties of a new systemic lupus erythematosus-specific quality-of- life instrument (SLEQOL). Ann Acad Med Singapore. 2004 Sep;33(5 Suppl):S35Leong KP, Kong KO, Thong BY, Koh ET, Lian TY, The CL, Cheng YK, Chng HH, Badsha H, Law WG, Lau TC, Chew LC, Ho HJ, Pong LY, Hoi LS, Nagarajan S, Chan SP, Howe HS.

14. Development and preliminary validation of a systemic lupus erythematosus-specific quality-of-life instrument (SLEQOL). Rheumatology (Oxford). 2005 Mar 29 Leong KP, Kong KO, Thong BY, Koh ET, Lian TY, Teh CL, Cheng YK, Chng HH, Badsha H, Law WG, Lau TC, Chew LC, Ho HJ, Pong LY, Hoi LS, Sangeetha N, Chan SP, Howe HS

15. Proinflammatory high-density lipoprotein as a biomarker for atherosclerosis in patients with systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum. 2006 Jul 25;54(8):2541-2549. Mc Mohan M, Grossman J, Fitzgerald J, Dahlin Lee E, Wallace DJ, Thong BY, Badsha H, Kalunian K, Charles C, Navab M, Fogelman AM, Hahn BH

16. Association of a common complement receptor 2 haplotype with increased risk of SLE. Proc. Natl. Acad. Sci. In press. Wu H, Boackle SA, Hanvivadhanaku P, Ulgiati D, Grossman JM, Lee Y,
Shen N, Abraham LJ, Mercer TR, Park E, Hebert LA, Rovin BH, Birmingham DJ, Chang D, Chen CJ, McCurdy D, Badsha HM, Thong BYH, Chng HH, Arnett FC, Wallace DJ, Yu CY, Hahn BH, Cantor RM, Tsao BP.

17. Rheumatoid arthritis in Dubai--delayed diagnosis and low usage of disease modifying antirheumatic drugs
Ann Rheum Dis. 2007 Jun;66(6):835 Badsha H, Kong KO, Tak PP

Book Chapters:

Badsha H, Rheumatoid Arthritis. A Clinical Approach to Medicine. 1st edition. Ong YY, Woo KT,

ABSTRACTS:

1. European league against rheumatology annual meetings. [ab0253] predictive model of mortality among patients admitted to a tertiary centre

Authors: T.Y. Lian 1, K.O. Kong 1, H. Badsha 1, C.L. Teh 1, H.H. Chng 1
Year: 2003

2. [Thu0150] Characteristics Of Patients Presenting With Inflammatory Arthritis To A Musculoskeletal Disease Clinic In Dubai

Authors: H. Badsha, P.P. Tak
Year: 2006

3. [Thu0151] Characteristics Of 357 Admissions Of Systemic Lupus Erythematosus Patients To A Rheumatology Department During One Year

Authors: C.J. Edwards 1, T.Y. Lian 2, H. Badsha 2, H.H. Chng 2
Year: 2002

4. [Thu0141] Risk Factors For Serious Infections In Lupus Nephritis Patients Treated With High Dose Prednisolone

Authors: K.O. Kong, T.Y. Lian, H. Badsha, H.H. Chng
Year: 2002

5. [Thu0043] Usefulness Of Serum Soluble Cd38 And Cd157 Levels In SLE And Ra - Relationship With Disease Activity

Authors: K. Kong 1, B. Leung 1, H. Chng 1, B. Thong 1, E. Koh 1, K. Leong 1, H. Badsha 1, T. Lian 1 , K. Khoo 1, H. Howe 1
Year: 2003

6. [Ab0281] Low Dose Pulse Methylprednisolone Is Effective Therapy For SLE Flares: A Prospective Study

Authors: T.Y. Lian 1, H. Badsha 1, K.O. Kong 1, C.J. Edwards 2, H.H. Chng 1
Year: 2003

7. [Ab0264] Changing Patterns Of Lupus Mortality In A Tertiary Centre In Singapore

Authors: W.G. Law 1, C.L. Teh 1, H. Badsha 1, T.Y. Lian 1, K.O. Kong 1, E.T. Koh 1, H.H. Chng 1
Year: 2003

8. [Thu0280] interferon-inducible protein 10 (ip-10) is a potential biomarker of disease activity in SLE

Authors: k.o. kong1, b.y.h. thong 1 , t.y. lian 1 , h.h. chng 1 , y.k. cheng 1 , c.l. teh 1 , e.t. koh 1 , w.g . Law 1 , w.h. yong 1 , l.c. chew 1 , t.c. lau 1 , h. Badsha 1 , k.p. leong 1 , b.p.l. leung 2 , h.s. howe 1
Year: 2006

AMERICAN COLLEGE OF RHEUMATOLOGY ANNUAL SCIENTIFIC MEETINGS

1997

A susceptibility gene for SLE maps to a 5 cM region of human chromosome 1q.

BP Tsao, RM Cantor, H Badsha, JM Grossman, KC Kalunian, H Hartung, FC Arnett, DJ Wallace, BH Hahn, JI Rotter.

Arthritis and Rheumatism, volume 40, No.9 (supplement)

2000
Pulmonary hypertension in systemic lupus erythematosus Treatment with Intermittent epoprostenol infusion

Kong KO, Badsha H, Thumboo J, Pao Hsii Feng

Arthritis and Rheumatism vol 43 No.9 (supplement)

2001
Pulse Methylprednisolone for SLE flares: A lower dose decreases the risk of serious infections without reducing efficacy

Badsha H; Kong KO; Lian TY; Chan SP; Edwards CJ; Chng HH

Arthritis and Rheumatism vol 44 No.9 (supplement) p. S280

2002Risk Factors for Serious Infections among Lupus Nephritis Patients Treated with High Dose Prednisolone
Category: 23 SLE—clinical aspects

Tsui Yee Lian, Kok Ooi Kong, Humeira Badsha, Hiok Hee Chng

Arthritis and Rheumatism vol 45 No.9 (supplement)

SLEDAI and SLAM are Useful Indicators of Disease Activity in Lupus Patients with Pulmonary Haemorrhage
Category: 23 SLE—clinical aspects
Humeira Badsha, Cheng Lay Teh, Kok Ooi Kong, Tsui Yee Lian, Hiok Hee Chng
Arthritis and Rheumatism vol 45 No.9 (supplement) p

2003
Markers In A 1-Mb Interval Within 1q23.3 Are Associated With Systemic Lupus Erythematosus Susceptibility
Hui Wu, Rita M. Cantor, Jennifer M. Grossman, Alexis A. Rumbin, Nan Shen , Chak S. Lau, Daniel J. Wallace, Frank C. Arnett, Humeira M. Badsha, Hiok H. Chng, Bevra H. Hahn, Betty P. Tsao

Arthritis and Rheumatism vol 46 No.9 (supplement) p

TGF Beta Polymorphisms and Serum TGF Levels in Oriental Patients with Ankylosing Spondylitis
Category: 27 Spondylarthropathies
Hwee Siew Howe , Po Loong Cheung, Kok Ooi Kong, Humeira Badsha, Bernard Thong, Khai Pang Leong, Tang Ching Lau, Ee Tzun Koh, Tsui Yee Lian , Yew Kuang Cheng, Diana Teo, Sally Lam, Bernard P. Leung.

Arthritis and Rheumatism vol 46 No.9 (supplement) p

2004
SLAM and SLEDAI are Valid Disease Activity Measures in Oriental Lupus Patients with SLEDAI being More Sensitive to Change
Kok Ooi Kong, Bernard YuHor Thong, Tsui Yee Lian, Cheng Lay Teh, Ee Tzun Koh, Yew Kuang Cheng, Hiok Hee Chng, Weng Giap Law, Tang Ching Lau, Humeira Badsha, Khai Pang Leong, Li Ching Chew, Hwee Siew Howe.

Arthritis and Rheumatism vol 47 No.9 (supplement) p

What Does Patient Global Assessment of Health Measure when SLE Patients are Asked to Evaluate their Own General Health?
Kok Ooi Kong, Bernard Yu Hor Thong, Tsui Yee Lian, Cheng Lay Teh, Ee Tzun Koh, Yew Kuang Cheng, Hiok Hee Chng, Weng Giap Law, Tang Ching Lau, Humeira Badsha, Khai Pang Leong, Li Ching Chew, Hwee Siew Howe.

Arthritis and Rheumatism vol 47 No.9 (supplement) p

Atherosclerosis in SLE May Relate to Abnormal Protective Capacity of HDL
Maureen A. McMahon1, Jennifer Grossman, John Fitzgerald, Fanny Ebling, Erika Dahlin-Lee, Bernard Thong, Kenneth Kalunian, Daniel J. Wallace, Humeira Badsha , Mohamad Navab, Alan M. Fogelman, Bevra H. Hahn. Hiok Hee Chng

Arthritis and Rheumatism vol 47 No.9 (supplement) p



Evidence for SLE Susceptibility Gene(s) at 1q32
Young Ho Lee, Hui Wu, Rita M. Cantor, Jennifer M. Grossman, Alexis A. Rumbin, Elly Park1, Nan Shen, Chung Jen Chen , Humeira M. Badsha, Bernard YH Thong, Hiok H. Chong, Daniel J. Wallace, Bevra H. Hahn, Betty P. Tsao

Arthritis and Rheumatism vol 47 No.9 (supplement) p.

2005
Interferon-Inducible protein 10 (IP-10) in SLE: A Potential Biomarker with Good Correlation with Disease Activity.

Kok Ooi Kong, Bernard Yu Hor Thong, Tsui Yee Lian, Hiok Hee Chng, Yew Kuang Cheng, Cheng Lay Teh, Ee Tzun Koh , Weng Giap Law, Wern Hui Yong, Li Ching Chew, Tang Ching Lau, Humeira Badsha, Khai Pang Leong, Bernard Pui Lam Leung, Hwee Siew Howe

Pro-Inflammatory HDL as a Biomarker for Atherosclerosis in SLE and RA

Author(s):
Maureen McMahon, Jennifer Grossman, John Fitzgerald, Erika Dahlin-Lee, Fanny Ebling, Bernard Thong, Humira Badsha , Daniel J. Wallace, Kenneth Kalunian, Bevra Hahn.

Arthritis and Rheumatism vol 48 No.9 (supplement) p

2006
Association of a Common Haplotype of Complement Receptor 2 (CR2) with Increased Risk of SLE

H. Wu, S. Boackle, P. Hanvivadhanakul, D. Ulgiati, J. Grossman, Y. Lee, N. Shen, L. Abraham, T. Mercer , E. Park, L. Hebert, B. Rovin, D. Birmingham, D. Chang, C. Chen, D. McCurdy, H. Badsha, B. Thong, H. Chng, F. Arnett, D. Wallace, C. Y Yu, B. Hahn, R. Cantor, B. Tsao.

Arthritis and Rheumatism vol 49 No.9 (supplement) p